The initial clinical data requirements for mCODE were driven by two use cases: Comparative Effectiveness Analysis and Cooperative Decision Making and Comparative Effectiveness Analysis with Next Generation Sequencing. Descriptions of the two use cases are below:
After initial development, in early 2019, an open survey was conducted to validate and prioritize the data elements from these cases. Further down-scoping was done based on whether the data would be stored or captured in an EHR, and if it would place undue documentation burden on clinicians.
Additionally, while mCODE ultimately is meant to be applicable across all types of cancer, the initial focus (and both use cases) has been on solid tumors.
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