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CodeX (Common Oncology Data Elements eXtensions) is a HL7 FHIR Accelerator that is building a community to accelerate interoperable data modeling and applications leading to step-change improvements in cancer patient care and research.

CodeX members are achieving interoperability by integrating the mCODE (minimal Common Oncology Data Elements) FHIR Implementation Guide -- a standard language for cancer data -- into existing and new applications. As a part of this effort, CodeX will also develop extensions to mCODE as needed for Use-Cases-based projects to be successful.

For background, see the more detailed overview. To stay up to date on all CodeX news, subscribe to the general mailing Listserv below.

Use Cases

A number of potential CodeX Use Cases are now in the Discovery phase. These are Use Cases that promise to substantially improve cancer care and research through community alignment around the use of mCODE and necessary extensions for the sharing of standardized, structured cancer data. Current and prospective CodeX members are reviewing and building out Use Cases that will become the first CodeX projects.

CodeX is also launching the mCODE Community of Practice to share best practices for basic mCODE implementation within EHRs for data collection and sharing across a growing number of use cases. 

Contact Steve Bratt or Greg Shemancik to join the conversation.


A warm welcome to CodeX’s Founding Members! CodeX is currently talking with tens of organizations who are interested in becoming members to enable Smarter Data in the Fight Against Caner. Contact Steve Bratt or Greg Shemancik to discuss membership options.


Building a community to accelerate the use of a common language for cancer data requires specialized, quality support. As this initiative rolls out, CodeX will document the roles and responsibilities for its Program/Project Management, Steering Committee, Operating Committee, and how CodeX will maintain architectural integrity and accelerate capabilities by training and sharing across the community.

HL7 has compiled an excellent resource on HL7 and its standards process and tools.

Check back in February for more information.


As CodeX Use Cases are prioritized and new projects are started, FHIR Implementation Guides, Best Practices and other projects will be linked here. Stay tuned.

Site Content

Recent Blog Posts

Dear CodeX Community Since our last update on mCODE and CodeX, the world has changed dramatically.  I hope you and yours are safe.  If you are on reading this, you also understand the impact that cancer has on those close to and far from you and yours. You understand the potential for a common language for cancer data to improve cancer care, research and policy, and to reduce burden and cost.…
Thanks to presenters Dr. Lawrence Shulman, Dr. Peter Gabriel of UPenn, Melanie Combs-Dyer - Director of Innovation at Mettle Solutions and Tyler Haydell - Senior Product Manager at Flatiron Health. The slides and a recording of the meeting can be found here. Please join the July 31, 2020 CodeX mCODE Community of Practice meeting on July 31, 2020, noon, where we will discuss the CodeX Oncology Clinical Pathways: Prior Authorization use case. We hope to see you there!
MITRE and the  HL7® FHIR® Accelerator CodeX Community invite you to a unique MITRE Listening Session on oncology clinical pathways and prior authorization of cancer therapies on June 26, 2020 from 10:00-11:30 EDT.  Oncology is a dynamic specialty with a rapid expansion of new therapies and tumor genomics.  Over the past five years the use of oncology clinical pathways became a standard approach to assist oncologists in treatment recommendations.…


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