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number of potential Active CodeX Use Case projects are projects where requirements, models, FHIR IGs, implementations and pilots are currently under development by interested stakeholders.

Potential future CodeX Use Cases which are now in the Discovery phase. These  Phase, where stakeholders are requested to engage, identify the biggest challenges and necessary participants, and to propose future Active Use Case projects.

All are Use Cases that promise to substantially improve cancer care and research through community alignment around the use of mCODE and necessary extensions for sharing of standard, structured cancer data. Current and prospective CodeX members are reviewing and building out the ideas listed in the table below. CodeX members will prioritize and ultimately select use cases Use Cases for development based on:

  1. Their potential Potential impact to fill a compelling and urgent need (value)
  2. How quickly value can be demonstrated through implementation and pilots (speed)
  3. How excited committed the community is to lead and participate provide resources (community drive)
We are also launching the mCODE Community of Practice as a proto-use-case around routine data collection and sharing of mCODE-based data through EHRs and other systems.

Contact Steve Bratt or Greg Shemancik to learn more about any of the Use Cases below. All are welcome to join the conversation CodeX/mCODE Community of Practice.

Use Cases in the Discovery Phase

Active CodeX Use Case Projects

Use Case


Usage/Implementation Notes

Community of PracticeThe mCODE Community of Practice is a group of health systems and other CodeX members working together to improve cancer care and research by developing best practices for implementing mCODE into production EHRs and other systems to improve cancer care and research.Participants in the CoP will become better equipped to leverage mCODE in health data systems for a variety of purposes, including use cases like those below
++ ExtractionEnable existing EHRs and other systems to provide cancer patient data that conforms to the standard defined by the mCODE FHIR IG. Defines a software engineering framework and reference implementation for health IT developers to retrieve and share mCODE conformant data from existing systems. Extraction is often discussed within the CodeX/mCODE Community of Practice and is critical for almost all of the use cases raised by the community to date.
Empowering Patients to Find Clinical TrialsImprove capability for patients to find clinical trials for which they may be eligible. Define and structure key trial enrollment criteria; incorporate into
EHRs and structured patient reported data workflows to improve reliability and automated matching capabilities, reducing manual data entry to find
clinical trials potentially important to patients.  

CodeX Use Cases in the Discovery Phase

Enable sharing of critical radiation therapy summary data for care coordination or data reuse (research, quality measurement, payer-required reporting).

Use Case


Usage/Implementation Notes

Cancer Registry ReportingEnable low-burden, standardized reporting of cancer data from cancer centers to registries that are aggregating data for different reasons.Consider use of mCODE and extensions for registry reporting to assess cross-center standards of care, starting with CAR-T therapy. Other potential scenarios could expand scope to support population health, clinical trials, post-market surveillance, quality reporting, comparative effectiveness and more.
Radiation Therapy Treatment Data for Care Coordination and Data Reuse

Enable sharing of critical radiation therapy treatment data for care coordination or data reuse (research, quality measurement, payer-required reporting).

Develop, test and deploy open data standards that enable interoperable, multi-purpose exchange of radiation treatment summary data for care coordination and data reuse.

Oncology Clinical Pathways (OCP)

Enable clinicians to use an oncology clinical pathway application that accurately navigates to recommended treatments using structured data in the EHR.

Define and structure clinical oncology data required to evaluate branch-points. Use mCode and CodeX to define data elements and incorporate the new data into existing workflows.

Clinical Cancer Data Exchange (CCDE)Oncology Clinical Pathways: Prior Authorization Support

Enable automatic exchange of clinical oncology data recorded by providers, to payers.

Da Vinci HL7 FHIR Accelerator has developed a solution for the generic use case. This use case extends the generic use case with mCODE and CodeX for provider-payer data exchange in support of care for cancer patients.
EHR Endpoints for Clinical Trials

Reduce and potentially eliminate manual and/or duplicate data entry into case report forms (CRF). 

Use clinical treatment data captured in the EHR to derive and/or compute clinical trial endpoints. mCODE and CodeX extensions support this data. Scenarios of interest include CAR-T therapies, rare diseases and others.
Alternative Payment Model Data ReportingFacilitate clinical practice reporting to registries and payer repositories governed by oncology payment models, such as chemotherapy episodes.Define and structure oncology APM required data using mCODE and CodeX extensions; incorporate into EHR workflows. 
Drug Value Based AgreementsOperationalize drug value based agreements for clinicians, payers, and pharma.  Define and structure relevant real world data using mCODE and CodeX extensions to enable collection in EHRs, making it available for automated outcome evaluation. Radiation Therapy Data for Care Coordination and Data ReuseProvider shares radiation therapy oncology treatment summary data with other providers, patients and authorized receivers. mCODE and potential CodeX data elements are incorporated into the radiation oncology workflows.