As mentioned on the Managing Specification Feedback page, only administrators have the power to mark an issue as "published". This will typically be done by doing a search that filters for all issues with the specified Specification that have a status of "Applied", then using the Bulk Changes mechanism to perform a Published transition on all of those issues.
Once all applied changes have been marked as 'published', all 'deferred' changes should be re-activated (also with a bulk change).
Administrators also have access to manage the specification feedback project itself - changing associated fields, screens, permissions, etc. This should only be done in coordination with HL7 staff. Instructions can be found on the page dealing with Maintaining Specification Feedback Projects.