Page tree
Skip to end of metadata
Go to start of metadata

The purpose of this CodeX Use Case Project Dashboard is to provide status updates for the most significant, overarching tasks associated with each Use Case. This dashboard will act to facilitate discussions regarding Use Case progress and performance for key tasks. CodeX Use Cases projects are in one of 3 stages:

  • CodeX Use Cases projects are in one of 3 stages, transitioned according to the Use Case Development Guidelines:

    • Use Cases are in the Discovery are ideas in the Backlog that have been proposed for future consideration, with a small group discussing, and aligning on a concept.
    • Use Cases in Active Community Planning are, as the name implies, being planned with Members - Identifying necessary stakeholders, objectives, deliverables, measures of success and schedules for fast-moving phases.
    • Use Case Projects in Active Community Execution are projects where models, mCODE-based FHIR IGs, implementations and pilots are currently under development, led by CodeX members.

Contact CodeX Program Management to learn more about any of the Use Cases below. Pre-Discovery and Archived Use Case Concepts can be found here. All are welcome to join the CodeX/mCODE Community of Practice to hear presentations on implementation work inside and outside of CodeX.

Use Cases and Objectives

Key Work Underway

Key Accomplishments

Active Community Execution



Cancer Registry Reporting

Enable reporting of mCODE-based cancer data from health center EHRs to a state and a private registry that are aggregating data for different reasons, substantially reducing duplication and burden while increasing reporting speed and accuracy.

COMPLETE Phase 0 - Collect requirements and build technical architecture needed for pilot activity - conveying essential patient data to registries in a timely/low burden way

COMPLETE Phase 0 - Health system(s) commitment for implementation, pilot activity completed

ON TRACK Begin phase 1 activities as outlined in the Cancer Registry Reporting section.

COMPLETE Phase 0 - Determine patient data to use

COMPLETE Phase 0 - Determine state registry endpoint for pilot

COMPLETE Phase 0 - Determine private registry endpoint for pilot

COMPLETE Phase 0 - Implement MedMorph reference architecture at a Health system and create plan definitions for a state and a private registry.

COMPLETE Phase 0 - Complete the data exchange between the health system and the state registry and the private registry, proving the underlying architecture. 

CANCELED Drafting PSS in FHIR IG Publishing Process - decided to publish under MedMorph as Content IG, separate PSS as needed

EHR Endpoints for Cancer Clinical Trials (ICAREdata)

Collect research-quality mCODE-based data in and share from EHRs to increase the value of real-world data for clinical trials, and reduce and potentially eliminate manual and/or duplicate data entry into case report forms. 

ON TRACK ICAREdata Phase 2 - 11 clinical trials participating in ICAREdata (5 activated embedded trials and 6 under the companion protocol). 10 health systems with contracts. 2 health systems currently sharing data to the ICAREdata infrastructure.

DELAYED ICAREdata Adverse Event Reporting - Drafted initial AE model in draft CTCAE IG and documented AE clinical workflow. Developed IT implementation tracker. Pursuing a no cost extension into 2023. Project will engage sites that have already completed or close to completion of The ICAREdata project to participate in the AE project. 

COMPLETE Draft FHIR IG 

COMPLETE Phase 1 – Demonstrated successful collection of Cancer Disease Status as a structured phrase in patient clinical note

COMPLETE Phase 2– An operational infrastructure with mCODE data flowing from health systems to the ICAREdata infrastructure


Integrated Trial Matching for Cancer Patients and Providers 

Leverage mCODE-based data standards and open APIs that enable interoperable, scalable, and accessible clinical trial matching services to improve the ability for patients to find clinical trials for which they may be eligible. 

DEFERRED Phase 2A – integration with PDMs and production clinical trial matching services, working with patient advocacy organizations to recruit patients to join application and test capability, expand to multiple cancer types and evaluate clinical trial matching service coverage

ON TRACK Phase 2B – expand data analysis to include additional patients and cancer types, integrate clinical trial matching at the point of care for prospective pilot 

COMPLETE Draft FHIR IG  

COMPLETE Phase 0 Pilot using synthetic data to find trials via one matching services (Report)

COMPLETE Trial Matching PSS approved by HL7 BR&R Workgroup and TSC

COMPLETE Phase 1A – integration with Cancer Insights, recruiting patients to join application and test capability, evaluating the optimized patient data elements

COMPLETE Phase 1B – use of retrospective patient data from UTSW and Massive Bio, evaluating the optimized patient data elements 

mCODE++ Extraction

Software to enable existing EHRs and other systems to share cancer patient data conformant to the mCODE FHIR IG, to support a variety of use cases.

ON TRACK Implementing Extraction framework to support the ICAREdata project within the EHR Endpoints for Cancer Clinical Trials use case. 

Radiation Therapy Treatment Data for Cancer

Leverage mCODE and extensions to enable sharing of critical radiation therapy treatment data for care coordination or data reuse (research, quality measurement, payer-required reporting).

ON TRACK Phase 3 – finalizing Prescription and Plan profiles and implement in XRTS technical spec and CodeX RT IG

ON TRACK Phase 4 – modeling RTTD team's defined list of Phase 4 data elements

ON TRACK Phase 3 – gathering all Sept. 2022 HL7 ballot comments, resolve negative comments, and update CodeX RT IG to reflect decisions

ON TRACK Phase 3 – Varian & RaySearch begin designing initial pilot with interested health site(s) – Michigan, VA, MD Anderson, UCSF, Penn

ON TRACK Phase 3 – Preparing for upcoming December 2022 IHE-RO Exchange of Radiotherapy Summaries (XRTS) Workshop


COMPLETE Phase 2 complete - Epic, Varian, and RaySearch implemented the radiotherapy profiles in the XRTS framework at the May 2022 XRTS Workshop

  • RTTD held a Public Call on July 19th, 2022 to provide project updates and upcoming plans

COMPLETE RayCare 6A supports the mCODE Radiotherapy Course Summary and Radiotherapy Volume

COMPLETE CodeX RT IG officially submitted to September 2022 Ballot Cycle




Active Community Planning



Prior Authorization in Oncology

Facilitate sharing of mCODE-based clinical data between providers and payers to reduce burden and speed authorization or requests for more information.

ON TRACK Phase 1 - Use case is in the Planning Phase 

Members (eviCore/Evernorth, Varian, Mettle Solutions, ASTRO, MCG, ONS, Telligen, McKesson/Ontada) have confirmed prostate radiation oncology pilot. 

McKesson has begun identifying clinical level practice management/workflow SMEs to engage in workflow evaluation, technical requirements and data.  They are focusing on synthetic data and test system for with a prime focus on prostate at this time (5.2022)

Bi-weekly technical team are progressing.  Workflow has been completed.  Identification of Data elements (demo graphics and clinical) has been completed (see below). 

IN PROGRESS Phase 1 - Test site system preparation by EHR/Varian and McKesson pilot sites

IN PROGRESS Phase 1 - Building of payer clinical questionnaire(s), CRD, DTR process

IN PROGRESS Phase 1 - Drafting of implementation documentation is progressing.   


Documentation found here - PA in Oncology - Documents


COMPLETE Develop an end-to-end proof of concept with full prior authorization in conformance with Da Vinci standards

COMPLETE  The proof of concept features the Da Vinci prior authorization information exchange with two synthetic cancer patients who have mCODE elements.  The exchange shows extraction of mCODE from the EHR via a SMART-on-FHIR application.  This data pre-populate the FHIR questionnaires used in interaction between provider and payer.

COMPLETE  Breast and Prostate use cases and champions identified.  Request to move to planning phase completed.  Phases of Planning and key efforts to accomplish have been identified and vetted with members and the public.  

COMPLETE Identification of test site piloter

COMPLETE New demonstration from implementer/developer, MCG, was completed 5.11.22.  See PA in Oncology - Documents for demo video

COMPLETE Evaluation of patient demographic and clinical data elements to be used in use case and gap analysis to mCode.  Initial evaluation has been done but with a deeper dive into the workflow to identify the need for PA, the data needed at each step, may alter the data elements needed or not needed.

COMPLETE Phase 0 Pilot metrics identified by members




Discovery



CardX - Hypertension Management

IN PROGRESS

Early member group defining problem, goals, value and scope

Engaging interested community members and preparing for public CodeX meetings to discuss the first CardX use case, develop a proposed solution/workflow, and identify end goal


GenomeX - FHIR Genomics Data Exchange

IN PROGRESS

Early member group defining problem, goals, value and scope

Engaging interested community members and preparing for public CodeX meetings to discuss the use case, develop a proposed solution/workflow, and identify end goal


GenomeX - Enabling Access to Complex Genomic Information through FHIR Genomics Operations

IN PROGRESS

Early member group defining problem, goals, value and scope

Engaging interested community members and preparing for public CodeX meetings to discuss the use case, develop a proposed solution/workflow, and identify end goal


Risk Evaluation and Mitigation Strategies

Create integrated, automated, efficient, and effective REMS programs by leveraging open data standards and creating the data infrastructure to enable REMS integration into the current workflow and data sharing across REMS stakeholders reducing undue burden 

IN PROGRESS

Members are in weekly discussions, aligning on use case focus of improving the provider, provider team workflows by automating and standardizing data and workflow processes.  

Public meetings are currently planned to be held monthly.   With the next public call tentatively scheduled for March 31st.  Monthly meetings have no been established for March - July 2022.  

REMS use case champions, FDA alongside ONS are presenting at March's Community of Practice


Quality Measures

Create a solution that demonstrates the ability to author and evaluate digital quality measures using the FHIR data model and mCODE, where applicable, for value-based programs and clinical quality improvement in the oncology domain


ON TRACK Preparing project materials to support transition from Pre-Discovery to Discovery. Focusing efforts on:

  1. New member orientation
  2. Discussing what moving to the Discovery Stage entails
  3. Reviewing the Use Case Development Guidelines page for next steps

COMPLETE CodeX Quality Measures Proposal approved by CodeX Steering Committee and use case officially moved to the Discovery Stage

On Hold

Oncology Clinical Pathways 

Enable clinicians to use an oncology clinical pathway applications that accurately navigates to recommended treatments using mCODE-based data from the EHR.



  • No labels